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In a large meta-analysis of randomized clinical trials by Chang and colleagues, a link was found between deficiency in omega-3 fatty acids EPA and DHA and attention deficit hyper disorder (ADHD) (Chang et al., 2018). Seven studies were included, where children or adolescents with an ADHD diagnosis received either a placebo or omega-3 fatty acid supplementation. The authors then assessed the effect of omega-3 fatty acid supplementation on cognitive scores, inattention clinical symptoms and ADHD clinical symptoms. Children and adolescents with ADHD were found to have lower levels of DHA, EPA and total omega-3 fatty acids. Importantly, supplementation with omega-3 fatty acids improves clinical symptoms and cognitive performances in children and adolescents with ADHD.
Click on the file below to download the article by Chang and colleagues. Reference Chang, J. P.-C., Su, K.-P., Mondelli, V., & Pariante, C. M. (2018). Omega-3 Polyunsaturated Fatty Acids in Youths with Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-Analysis of Clinical Trials and Biological Studies. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology, 43(3), 534–545. https://doi.org/10.1038/npp.2017.160 |
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| Chang et al (2018) Omega-3 Polyunsaturated Fatty Acids in Youths with Attention Deficit Hyperactivity Disorder |
